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The CspC pseudoprotease regulates germination of Clostridioides difficile spores in response to multiple environmental signals

The gastrointestinal pathogen, Clostridioides difficile, initiates infection when its metabolically dormant spore form germinates in the mammalian gut. While most spore-forming bacteria use transmembrane germinant receptors to sense nutrient germinants, C. difficile is thought to use the soluble pse...

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Detalles Bibliográficos
Autores principales: Rohlfing, Amy E., Eckenroth, Brian E., Forster, Emily R., Kevorkian, Yuzo, Donnelly, M. Lauren, Benito de la Puebla, Hector, Doublié, Sylvie, Shen, Aimee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636752/
https://www.ncbi.nlm.nih.gov/pubmed/31276487
http://dx.doi.org/10.1371/journal.pgen.1008224