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The CspC pseudoprotease regulates germination of Clostridioides difficile spores in response to multiple environmental signals
The gastrointestinal pathogen, Clostridioides difficile, initiates infection when its metabolically dormant spore form germinates in the mammalian gut. While most spore-forming bacteria use transmembrane germinant receptors to sense nutrient germinants, C. difficile is thought to use the soluble pse...
Autores principales: | Rohlfing, Amy E., Eckenroth, Brian E., Forster, Emily R., Kevorkian, Yuzo, Donnelly, M. Lauren, Benito de la Puebla, Hector, Doublié, Sylvie, Shen, Aimee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636752/ https://www.ncbi.nlm.nih.gov/pubmed/31276487 http://dx.doi.org/10.1371/journal.pgen.1008224 |
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