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Immunoproteomic analysis of a Chikungunya poxvirus-based vaccine reveals high HLA class II immunoprevalence

BACKGROUND: Efficient adaptive antiviral cellular and humoral immune responses require previous recognition of viral antigenic peptides bound to human leukocyte antigen (HLA) class I and II molecules, which are exposed on the surface of infected and antigen presenting cells, respectively. The HLA-re...

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Detalles Bibliográficos
Autores principales: Lorente, Elena, Barriga, Alejandro, Barnea, Eilon, Palomo, Concepción, García-Arriaza, Juan, Mir, Carmen, Esteban, Mariano, Admon, Arie, López, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636782/
https://www.ncbi.nlm.nih.gov/pubmed/31276466
http://dx.doi.org/10.1371/journal.pntd.0007547