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Sox2 and FGF20 interact to regulate organ of Corti hair cell and supporting cell development in a spatially-graded manner

The mouse organ of Corti, housed inside the cochlea, contains hair cells and supporting cells that transduce sound into electrical signals. These cells develop in two main steps: progenitor specification followed by differentiation. Fibroblast Growth Factor (FGF) signaling is important in this devel...

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Detalles Bibliográficos
Autores principales: Yang, Lu M., Cheah, Kathryn S. E., Huh, Sung-Ho, Ornitz, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636783/
https://www.ncbi.nlm.nih.gov/pubmed/31276493
http://dx.doi.org/10.1371/journal.pgen.1008254