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Sox2 and FGF20 interact to regulate organ of Corti hair cell and supporting cell development in a spatially-graded manner
The mouse organ of Corti, housed inside the cochlea, contains hair cells and supporting cells that transduce sound into electrical signals. These cells develop in two main steps: progenitor specification followed by differentiation. Fibroblast Growth Factor (FGF) signaling is important in this devel...
Autores principales: | Yang, Lu M., Cheah, Kathryn S. E., Huh, Sung-Ho, Ornitz, David M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636783/ https://www.ncbi.nlm.nih.gov/pubmed/31276493 http://dx.doi.org/10.1371/journal.pgen.1008254 |
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