B Cell Fcγ Receptor IIb Modulates Atherosclerosis in Male and Female Mice by Controlling Adaptive Germinal Center and Innate B-1-Cell Responses

OBJECTIVE—: Investigate the impact of modulating B cell FcγRIIb (Fcγ receptor IIb) expression on atherosclerosis. APPROACH AND RESULTS—: Western diet–induced atherosclerosis was assessed in Ldlr(−)(/−) or Apoe(−/−) mice with B cell–specific overexpression of FcγRIIb or with an FcγRIIb promoter mutat...

Descripción completa

Detalles Bibliográficos
Autores principales: Bagchi-Chakraborty, Jayashree, Francis, Anna, Bray, Toni, Masters, Leanne, Tsiantoulas, Dimitrios, Nus, Meritxell, Harrison, James, Broekhuizen, Michelle, Leggat, Jennifer, Clatworthy, Menna R., Espéli, Marion, Smith, Kenneth G.C., Binder, Christoph J., Mallat, Ziad, Sage, Andrew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2019
Materias:
Basic Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636804/
https://www.ncbi.nlm.nih.gov/pubmed/31092015
http://dx.doi.org/10.1161/ATVBAHA.118.312272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636804/
https://www.ncbi.nlm.nih.gov/pubmed/31092015
http://dx.doi.org/10.1161/ATVBAHA.118.312272

Ejemplares similares