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B Cell Fcγ Receptor IIb Modulates Atherosclerosis in Male and Female Mice by Controlling Adaptive Germinal Center and Innate B-1-Cell Responses

OBJECTIVE—: Investigate the impact of modulating B cell FcγRIIb (Fcγ receptor IIb) expression on atherosclerosis. APPROACH AND RESULTS—: Western diet–induced atherosclerosis was assessed in Ldlr(−)(/−) or Apoe(−/−) mice with B cell–specific overexpression of FcγRIIb or with an FcγRIIb promoter mutat...

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Detalles Bibliográficos
Autores principales:	Bagchi-Chakraborty, Jayashree, Francis, Anna, Bray, Toni, Masters, Leanne, Tsiantoulas, Dimitrios, Nus, Meritxell, Harrison, James, Broekhuizen, Michelle, Leggat, Jennifer, Clatworthy, Menna R., Espéli, Marion, Smith, Kenneth G.C., Binder, Christoph J., Mallat, Ziad, Sage, Andrew P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2019
Materias:	Basic Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636804/ https://www.ncbi.nlm.nih.gov/pubmed/31092015 http://dx.doi.org/10.1161/ATVBAHA.118.312272

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