Determining population stratification and subgroup effects in association studies of rare genetic variants for nicotine dependence

BACKGROUND: Rare variants (minor allele frequency < 1% or 5 %) can help researchers to deal with the confounding issue of ‘missing heritability’ and have a proven role in dissecting the etiology for human diseases and complex traits. METHODS: We extended the combined multivariate and collapsing (...

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Detalles Bibliográficos
Autores principales: Hsieh, Ai-Ru, Chen, Li-Shiun, Li, Ying-Ju, Fann, Cathy S.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636808/
https://www.ncbi.nlm.nih.gov/pubmed/31033776
http://dx.doi.org/10.1097/YPG.0000000000000227

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636808/
https://www.ncbi.nlm.nih.gov/pubmed/31033776
http://dx.doi.org/10.1097/YPG.0000000000000227

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