Cargando…
Determining population stratification and subgroup effects in association studies of rare genetic variants for nicotine dependence
BACKGROUND: Rare variants (minor allele frequency < 1% or 5 %) can help researchers to deal with the confounding issue of ‘missing heritability’ and have a proven role in dissecting the etiology for human diseases and complex traits. METHODS: We extended the combined multivariate and collapsing (...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Lippincott Williams & Wilkins
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636808/ https://www.ncbi.nlm.nih.gov/pubmed/31033776 http://dx.doi.org/10.1097/YPG.0000000000000227 |