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Differential Sensitivity to IL-12 Drives Sex-Specific Differences in the CD8+ T Cell Response to Infection

It is well known that males and females respond differently to intracellular pathogens. Females mount a more robust immune response than males, which decreases their susceptibility to infection but comes at the cost of increasing immunopathology. However, the underlying basis for sex-specific differ...

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Detalles Bibliográficos
Autores principales: Yee Mon, Kristel Joy, Goldsmith, Elizabeth, Watson, Neva B., Wang, Jocelyn, Smith, Norah L., Rudd, Brian D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636834/
https://www.ncbi.nlm.nih.gov/pubmed/31317126
http://dx.doi.org/10.4049/immunohorizons.1800066