An injectable bone marrow–like scaffold enhances T cell immunity after hematopoietic stem cell transplantation

The use of allogeneic hematopoietic stem cell transplantation (HSCT) to cure multiple disorders is limited by deficiency and dysregulation of T-cells. Here we report a biomaterial-based scaffold that mimics features of T-cell lymphopoiesis in the bone marrow. The bone marrow cryogel (BMC) releases b...

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Detalles Bibliográficos
Autores principales: Shah, Nisarg J., Mao, Angelo S., Shih, Ting-Yu, Kerr, Matthew D., Sharda, Azeem, Raimondo, Theresa M., Weaver, James C., Vrbanac, Vladimir D., Deruaz, Maud, Tager, Andrew M., Mooney, David J., Scadden, David T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636841/
https://www.ncbi.nlm.nih.gov/pubmed/30742125
http://dx.doi.org/10.1038/s41587-019-0017-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636841/
https://www.ncbi.nlm.nih.gov/pubmed/30742125
http://dx.doi.org/10.1038/s41587-019-0017-2

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