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FOXA2 Is Required for Enhancer Priming during Pancreatic Differentiation

Transcriptional regulatory mechanisms of lineage priming in embryonic development are largely uncharacterized because of the difficulty of isolating transient progenitor populations. Directed differentiation of human pluripotent stem cells (hPSCs) combined with gene editing provides a powerful syste...

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Detalles Bibliográficos
Autores principales: Lee, Kihyun, Cho, Hyunwoo, Rickert, Robert W., Li, Qing V., Pulecio, Julian, Leslie, Christina S., Huangfu, Danwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636862/
https://www.ncbi.nlm.nih.gov/pubmed/31291575
http://dx.doi.org/10.1016/j.celrep.2019.06.034