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FOXA2 Is Required for Enhancer Priming during Pancreatic Differentiation
Transcriptional regulatory mechanisms of lineage priming in embryonic development are largely uncharacterized because of the difficulty of isolating transient progenitor populations. Directed differentiation of human pluripotent stem cells (hPSCs) combined with gene editing provides a powerful syste...
Autores principales: | Lee, Kihyun, Cho, Hyunwoo, Rickert, Robert W., Li, Qing V., Pulecio, Julian, Leslie, Christina S., Huangfu, Danwei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636862/ https://www.ncbi.nlm.nih.gov/pubmed/31291575 http://dx.doi.org/10.1016/j.celrep.2019.06.034 |
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