The prostate cancer risk variant rs55958994 regulates multiple gene expression through extreme long-range chromatin interaction to control tumor progression

Genome-wide association studies identified single-nucleotide polymorphism (SNP) rs55958994 as a significant variant associated with increased susceptibility to prostate cancer. However, the mechanisms by which this SNP mediates increased risk to cancer are still unknown. In this study, we show that...

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Detalles Bibliográficos
Autores principales: Qian, Yuyang, Zhang, Lei, Cai, Mingyang, Li, Hongxia, Xu, Heming, Yang, Hongzhen, Zhao, Zhongfang, Rhie, Suhn Kyong, Farnham, Peggy J., Shi, Jiandang, Lu, Wange
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636982/
https://www.ncbi.nlm.nih.gov/pubmed/31328168
http://dx.doi.org/10.1126/sciadv.aaw6710

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636982/
https://www.ncbi.nlm.nih.gov/pubmed/31328168
http://dx.doi.org/10.1126/sciadv.aaw6710

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