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The prostate cancer risk variant rs55958994 regulates multiple gene expression through extreme long-range chromatin interaction to control tumor progression
Genome-wide association studies identified single-nucleotide polymorphism (SNP) rs55958994 as a significant variant associated with increased susceptibility to prostate cancer. However, the mechanisms by which this SNP mediates increased risk to cancer are still unknown. In this study, we show that...
Autores principales: | Qian, Yuyang, Zhang, Lei, Cai, Mingyang, Li, Hongxia, Xu, Heming, Yang, Hongzhen, Zhao, Zhongfang, Rhie, Suhn Kyong, Farnham, Peggy J., Shi, Jiandang, Lu, Wange |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636982/ https://www.ncbi.nlm.nih.gov/pubmed/31328168 http://dx.doi.org/10.1126/sciadv.aaw6710 |
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