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The orphan nuclear receptor LRH-1/NR5a2 critically regulates T cell functions

LRH-1 (liver receptor homolog-1/NR5a2) is an orphan nuclear receptor, which regulates glucose and lipid metabolism, as well as intestinal inflammation via the transcriptional control of intestinal glucocorticoid synthesis. Predominantly expressed in epithelial cells, its expression and role in immun...

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Detalles Bibliográficos
Autores principales: Seitz, Carina, Huang, Juan, Geiselhöringer, Anna-Lena, Galbani-Bianchi, Pamela, Michalek, Svenja, Phan, Truong San, Reinhold, Cindy, Dietrich, Lea, Schmidt, Christian, Corazza, Nadia, Delgado, M. Eugenia, Schnalzger, Theresa, Schoonjans, Kristina, Brunner, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636985/
https://www.ncbi.nlm.nih.gov/pubmed/31328159
http://dx.doi.org/10.1126/sciadv.aav9732