Cargando…
Functional cross-talk between allosteric effects of activating and inhibiting ligands underlies PKM2 regulation
Several enzymes can simultaneously interact with multiple intracellular metabolites, however, how the allosteric effects of distinct ligands are integrated to coordinately control enzymatic activity remains poorly understood. We addressed this question using, as a model system, the glycolytic enzyme...
| Autores principales: | , , , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636998/ https://www.ncbi.nlm.nih.gov/pubmed/31264961 http://dx.doi.org/10.7554/eLife.45068 |