Hypoxia-induced Downregulation of SRC-3 Suppresses Trophoblastic Invasion and Migration Through Inhibition of the AKT/mTOR Pathway: Implications for the Pathogenesis of Preeclampsia

Preeclampsia (PE) is characterized by poor placentation, consequent on aberrant extravillous trophoblast (EVT) cell function during placental development. The SRC family of proteins is important during pregnancy, especially SRC-3, which regulates placental morphogenesis and embryo survival. Although...

Descripción completa

Detalles Bibliográficos
Autores principales: He, Chengjin, Shan, Nan, Xu, Ping, Ge, Huisheng, Yuan, Yu, Liu, Yangming, Zhang, Pu, Wen, Li, Zhang, Fumei, Xiong, Liling, Peng, Chuan, Qi, Hongbo, Tong, Chao, Baker, Philip N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637123/
https://www.ncbi.nlm.nih.gov/pubmed/31316078
http://dx.doi.org/10.1038/s41598-019-46699-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637123/
https://www.ncbi.nlm.nih.gov/pubmed/31316078
http://dx.doi.org/10.1038/s41598-019-46699-3

Ejemplares similares