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Changes in nuclear and cytoplasmic microRNA distribution in response to hypoxic stress

MicroRNAs (miRNAs) are small non-coding RNAs that have well-characterized roles in cytoplasmic gene regulation, where they act by binding to mRNA transcripts and inhibiting their translation (i.e. post-transcriptional gene silencing, PTGS). However, miRNAs have also been implicated in transcriptiona...

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Detalles Bibliográficos
Autores principales: Turunen, Tiia A., Roberts, Thomas C., Laitinen, Pia, Väänänen, Mari-Anna, Korhonen, Paula, Malm, Tarja, Ylä-Herttuala, Seppo, Turunen, Mikko P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637125/
https://www.ncbi.nlm.nih.gov/pubmed/31316122
http://dx.doi.org/10.1038/s41598-019-46841-1