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High-throughput stability screening for detergent-solubilized membrane proteins

Protein stability in detergent or membrane-like environments is the bottleneck for structural studies on integral membrane proteins (IMP). Irrespective of the method to study the structure of an IMP, detergent solubilization from the membrane is usually the first step in the workflow. Here, we estab...

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Detalles Bibliográficos
Autores principales: Kotov, Vadim, Bartels, Kim, Veith, Katharina, Josts, Inokentijs, Subhramanyam, Udaya K. Tiruttani, Günther, Christian, Labahn, Jörg, Marlovits, Thomas C., Moraes, Isabel, Tidow, Henning, Löw, Christian, Garcia-Alai, Maria M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637136/
https://www.ncbi.nlm.nih.gov/pubmed/31316088
http://dx.doi.org/10.1038/s41598-019-46686-8