Analysis of the 4q35 chromatin organization reveals distinct long-range interactions in patients affected with Facio-Scapulo-Humeral Dystrophy

Facio-Scapulo Humeral dystrophy (FSHD) is the third most common myopathy, affecting 1 amongst 10,000 individuals (FSHD1, OMIM #158900). This autosomal dominant pathology is associated in 95% of cases with genetic and epigenetic alterations in the subtelomeric region at the extremity of the long arm...

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Detalles Bibliográficos
Autores principales: Gaillard, Marie-Cécile, Broucqsault, Natacha, Morere, Julia, Laberthonnière, Camille, Dion, Camille, Badja, Cherif, Roche, Stéphane, Nguyen, Karine, Magdinier, Frédérique, Robin, Jérôme D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637155/
https://www.ncbi.nlm.nih.gov/pubmed/31316120
http://dx.doi.org/10.1038/s41598-019-46861-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637155/
https://www.ncbi.nlm.nih.gov/pubmed/31316120
http://dx.doi.org/10.1038/s41598-019-46861-x

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