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Systematic evaluation of library preparation methods and sequencing platforms for high-throughput whole genome bisulfite sequencing
Whole genome bisulfite sequencing (WGBS), with its ability to interrogate methylation status at single CpG site resolution epigenome-wide, is a powerful technique for use in molecular experiments. Here, we aim to advance strategies for accurate and efficient WGBS for application in future large-scal...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637168/ https://www.ncbi.nlm.nih.gov/pubmed/31316107 http://dx.doi.org/10.1038/s41598-019-46875-5 |