Cargando…

Systematic evaluation of library preparation methods and sequencing platforms for high-throughput whole genome bisulfite sequencing

Whole genome bisulfite sequencing (WGBS), with its ability to interrogate methylation status at single CpG site resolution epigenome-wide, is a powerful technique for use in molecular experiments. Here, we aim to advance strategies for accurate and efficient WGBS for application in future large-scal...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Li, Ng, Hong Kiat, Drautz-Moses, Daniela I., Schuster, Stephan C., Beck, Stephan, Kim, Changhoon, Chambers, John Campbell, Loh, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637168/
https://www.ncbi.nlm.nih.gov/pubmed/31316107
http://dx.doi.org/10.1038/s41598-019-46875-5