Notch Inhibition Prevents Differentiation of Human Limbal Stem/Progenitor Cells in vitro

Notch signaling has been shown to regulate the homeostasis and wound healing of the corneal epithelium. We investigated the effect of Notch inhibition in the human limbal stem/progenitor cells (LSCs) in vitro by using small molecules. Treatment of the LSCs with DAPT and SAHM1 reduced the proliferati...

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Detalles Bibliográficos
Autores principales: González, Sheyla, Uhm, Heui, Deng, Sophie X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637172/
https://www.ncbi.nlm.nih.gov/pubmed/31316119
http://dx.doi.org/10.1038/s41598-019-46793-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637172/
https://www.ncbi.nlm.nih.gov/pubmed/31316119
http://dx.doi.org/10.1038/s41598-019-46793-6

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