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Notch Inhibition Prevents Differentiation of Human Limbal Stem/Progenitor Cells in vitro
Notch signaling has been shown to regulate the homeostasis and wound healing of the corneal epithelium. We investigated the effect of Notch inhibition in the human limbal stem/progenitor cells (LSCs) in vitro by using small molecules. Treatment of the LSCs with DAPT and SAHM1 reduced the proliferati...
Autores principales: | González, Sheyla, Uhm, Heui, Deng, Sophie X. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637172/ https://www.ncbi.nlm.nih.gov/pubmed/31316119 http://dx.doi.org/10.1038/s41598-019-46793-6 |
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