Establishment and equilibrium levels of deleterious mutations in large populations

Analytical and statistical stochastic approaches are used to model the dispersion of monogenic variants through large populations. These approaches are used to quantify the magnitude of the selective advantage of a monogenic heterozygous variant in the presence of a homozygous disadvantage. Dunbar’s...

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Detalles Bibliográficos
Autores principales: Viljoen, Johan W., de Villiers, J. Pieter, van Zyl, Augustinus J., Mezzavilla, Massimo, Pepper, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637196/
https://www.ncbi.nlm.nih.gov/pubmed/31316137
http://dx.doi.org/10.1038/s41598-019-46803-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637196/
https://www.ncbi.nlm.nih.gov/pubmed/31316137
http://dx.doi.org/10.1038/s41598-019-46803-7

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