Improved detection of common variants in coronary artery disease and blood pressure using a pleiotropy cFDR method

Plenty of genome-wide association studies (GWASs) have identified numerous single nucleotide polymorphisms (SNPs) for coronary artery disease (CAD) and blood pressure (BP). However, these SNPs only explain a small proportion of the heritability of two traits/diseases. Although high BP is a major ris...

Descripción completa

Detalles Bibliográficos
Autores principales: Mao, Xiang-Jie, Zhang, Qiang, Xu, Fei, Gao, Pan, Sun, Nan, Wang, Bo, Tang, Qi-Xin, Hao, Yi-Bin, Sun, Chang-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637206/
https://www.ncbi.nlm.nih.gov/pubmed/31316127
http://dx.doi.org/10.1038/s41598-019-46808-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637206/
https://www.ncbi.nlm.nih.gov/pubmed/31316127
http://dx.doi.org/10.1038/s41598-019-46808-2

Ejemplares similares