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Improved detection of common variants in coronary artery disease and blood pressure using a pleiotropy cFDR method
Plenty of genome-wide association studies (GWASs) have identified numerous single nucleotide polymorphisms (SNPs) for coronary artery disease (CAD) and blood pressure (BP). However, these SNPs only explain a small proportion of the heritability of two traits/diseases. Although high BP is a major ris...
Autores principales: | Mao, Xiang-Jie, Zhang, Qiang, Xu, Fei, Gao, Pan, Sun, Nan, Wang, Bo, Tang, Qi-Xin, Hao, Yi-Bin, Sun, Chang-Qing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637206/ https://www.ncbi.nlm.nih.gov/pubmed/31316127 http://dx.doi.org/10.1038/s41598-019-46808-2 |
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