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Fluorescence Imaging of Actin Turnover Parses Early Stem Cell Lineage Divergence and Senescence

This study describes a new approach to discern early divergence in stem cell lineage progression via temporal dynamics of the cytoskeletal protein, F-actin. The approach involves real-time labeling of human mesenchymal stem cells (MSCs) and longitudinal tracking of the turnover dynamics of a fluorog...

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Detalles Bibliográficos
Autores principales: Mishra, Prakhar, Martin, Daniel C., Androulakis, Ioannis P., Moghe, Prabhas V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637207/
https://www.ncbi.nlm.nih.gov/pubmed/31316098
http://dx.doi.org/10.1038/s41598-019-46682-y