NASC-seq monitors RNA synthesis in single cells

Sequencing of newly synthesised RNA can monitor transcriptional dynamics with great sensitivity and high temporal resolution, but is currently restricted to populations of cells. Here, we develop new transcriptome alkylation-dependent single-cell RNA sequencing (NASC-seq), to monitor newly synthesis...

Descripción completa

Detalles Bibliográficos
Autores principales: Hendriks, Gert-Jan, Jung, Lisa A., Larsson, Anton J. M., Lidschreiber, Michael, Andersson Forsman, Oscar, Lidschreiber, Katja, Cramer, Patrick, Sandberg, Rickard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637240/
https://www.ncbi.nlm.nih.gov/pubmed/31316066
http://dx.doi.org/10.1038/s41467-019-11028-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637240/
https://www.ncbi.nlm.nih.gov/pubmed/31316066
http://dx.doi.org/10.1038/s41467-019-11028-9

Ejemplares similares