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NASC-seq monitors RNA synthesis in single cells
Sequencing of newly synthesised RNA can monitor transcriptional dynamics with great sensitivity and high temporal resolution, but is currently restricted to populations of cells. Here, we develop new transcriptome alkylation-dependent single-cell RNA sequencing (NASC-seq), to monitor newly synthesis...
Autores principales: | Hendriks, Gert-Jan, Jung, Lisa A., Larsson, Anton J. M., Lidschreiber, Michael, Andersson Forsman, Oscar, Lidschreiber, Katja, Cramer, Patrick, Sandberg, Rickard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637240/ https://www.ncbi.nlm.nih.gov/pubmed/31316066 http://dx.doi.org/10.1038/s41467-019-11028-9 |
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