Intrinsic dynamic behavior of enzyme:substrate complexes govern the catalytic action of β-galactosidases across clan GH-A

The conformational itineraries taken by carbohydrate residues in the catalytic subsite of retaining glycoside hydrolases (GHs), harness the link between substrate conformation and reactivity. GHs’ active sites may be described as a combination of subsites dedicated to the binding of individual sugar...

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Detalles Bibliográficos
Autores principales: Kumar, Rajender, Henrissat, Bernard, Coutinho, Pedro M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637243/
https://www.ncbi.nlm.nih.gov/pubmed/31316086
http://dx.doi.org/10.1038/s41598-019-46589-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637243/
https://www.ncbi.nlm.nih.gov/pubmed/31316086
http://dx.doi.org/10.1038/s41598-019-46589-8

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