Complement Factor H Modulates Splenic B Cell Development and Limits Autoantibody Production

Complement factor H (CFH) has a pivotal role in regulating alternative complement activation through its ability to inhibit the cleavage of the central complement component C3, which links innate and humoral immunity. However, insights into the role of CFH in B cell biology are limited. Here, we dem...

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Detalles Bibliográficos
Autores principales: Kiss, Máté G., Ozsvár-Kozma, Mária, Porsch, Florentina, Göderle, Laura, Papac-Miličević, Nikolina, Bartolini-Gritti, Barbara, Tsiantoulas, Dimitrios, Pickering, Matthew C., Binder, Christoph J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637296/
https://www.ncbi.nlm.nih.gov/pubmed/31354740
http://dx.doi.org/10.3389/fimmu.2019.01607

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637296/
https://www.ncbi.nlm.nih.gov/pubmed/31354740
http://dx.doi.org/10.3389/fimmu.2019.01607

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