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Complement Factor H Modulates Splenic B Cell Development and Limits Autoantibody Production
Complement factor H (CFH) has a pivotal role in regulating alternative complement activation through its ability to inhibit the cleavage of the central complement component C3, which links innate and humoral immunity. However, insights into the role of CFH in B cell biology are limited. Here, we dem...
Autores principales: | Kiss, Máté G., Ozsvár-Kozma, Mária, Porsch, Florentina, Göderle, Laura, Papac-Miličević, Nikolina, Bartolini-Gritti, Barbara, Tsiantoulas, Dimitrios, Pickering, Matthew C., Binder, Christoph J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637296/ https://www.ncbi.nlm.nih.gov/pubmed/31354740 http://dx.doi.org/10.3389/fimmu.2019.01607 |
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