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Powerful testing via hierarchical linkage disequilibrium in haplotype association studies
Marginal tests based on individual SNPs are routinely used in genetic association studies. Studies have shown that haplotype‐based methods may provide more power in disease mapping than methods based on single markers when, for example, multiple disease‐susceptibility variants occur within the same...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637384/ https://www.ncbi.nlm.nih.gov/pubmed/30693553 http://dx.doi.org/10.1002/bimj.201800053 |