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Powerful testing via hierarchical linkage disequilibrium in haplotype association studies

Marginal tests based on individual SNPs are routinely used in genetic association studies. Studies have shown that haplotype‐based methods may provide more power in disease mapping than methods based on single markers when, for example, multiple disease‐susceptibility variants occur within the same...

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Detalles Bibliográficos
Autores principales: Balliu, Brunilda, Houwing‐Duistermaat, Jeanine J., Böhringer, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637384/
https://www.ncbi.nlm.nih.gov/pubmed/30693553
http://dx.doi.org/10.1002/bimj.201800053