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Do We Need Anti-Prionic Compounds to Treat Alzheimer’s Disease?

Background: While phase III clinical trials for the treatment of Alzheimer’s disease (AD) keep failing regardless of the target, more and more data suggest that the toxic protein assemblies of amyloid-beta protein (Aβ) and tubulin binding protein (TAU) behave like prions. Irrespective of the questio...

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Detalles Bibliográficos
Autores principales: Willbold, Dieter, Kutzsche, Janine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637388/
https://www.ncbi.nlm.nih.gov/pubmed/31208037
http://dx.doi.org/10.3390/molecules24122237