Cargando…
Do We Need Anti-Prionic Compounds to Treat Alzheimer’s Disease?
Background: While phase III clinical trials for the treatment of Alzheimer’s disease (AD) keep failing regardless of the target, more and more data suggest that the toxic protein assemblies of amyloid-beta protein (Aβ) and tubulin binding protein (TAU) behave like prions. Irrespective of the questio...
Autores principales: | Willbold, Dieter, Kutzsche, Janine |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637388/ https://www.ncbi.nlm.nih.gov/pubmed/31208037 http://dx.doi.org/10.3390/molecules24122237 |
Ejemplares similares
-
TDP-43 Pathology and Prionic Behavior in Human Cellular Models of Alzheimer’s Disease Patients
por: Cuevas, Eva P., et al.
Publicado: (2022) -
Could α-Synuclein Amyloid-Like Aggregates Trigger a Prionic Neuronal Invasion?
por: Busquets, Maria Antònia, et al.
Publicado: (2015) -
In Vitro and In Vivo Efficacies of the Linear and the Cyclic Version of an All-d-Enantiomeric Peptide Developed for the Treatment of Alzheimer’s Disease
por: Schemmert, Sarah, et al.
Publicado: (2021) -
Large-Scale Oral Treatment Study with the Four Most Promising D3-Derivatives for the Treatment of Alzheimer’s Disease
por: Kutzsche, Janine, et al.
Publicado: (2017) -
Oral Treatment with d-RD2RD2 Impedes Early Disease Mechanisms in SOD1*G93A Transgenic Mice but Does Not Prolong Survival
por: Wintz, Katharina, et al.
Publicado: (2023)