CellSIUS provides sensitive and specific detection of rare cell populations from complex single-cell RNA-seq data

We develop CellSIUS (Cell Subtype Identification from Upregulated gene Sets) to fill a methodology gap for rare cell population identification for scRNA-seq data. CellSIUS outperforms existing algorithms for specificity and selectivity for rare cell types and their transcriptomic signature identific...

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Detalles Bibliográficos
Autores principales: Wegmann, Rebekka, Neri, Marilisa, Schuierer, Sven, Bilican, Bilada, Hartkopf, Huyen, Nigsch, Florian, Mapa, Felipa, Waldt, Annick, Cuttat, Rachel, Salick, Max R., Raymond, Joe, Kaykas, Ajamete, Roma, Guglielmo, Keller, Caroline Gubser
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637521/
https://www.ncbi.nlm.nih.gov/pubmed/31315641
http://dx.doi.org/10.1186/s13059-019-1739-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637521/
https://www.ncbi.nlm.nih.gov/pubmed/31315641
http://dx.doi.org/10.1186/s13059-019-1739-7

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