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Multilayered control of exon acquisition permits the emergence of novel forms of regulatory control

BACKGROUND: The long introns of mammals are pools of evolutionary potential due to the multiplicity of sequences that permit the acquisition of novel exons. However, the permissibility of genes to this type of acquisition and its influence on the evolution of cell regulation is poorly understood. RE...

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Detalles Bibliográficos
Autores principales: Avgan, Nesli, Wang, Juli I., Fernandez-Chamorro, Javier, Weatheritt, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637531/
https://www.ncbi.nlm.nih.gov/pubmed/31315652
http://dx.doi.org/10.1186/s13059-019-1757-5