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LIMK1 and LIMK2 regulate cortical development through affecting neural progenitor cell proliferation and migration

LIMK1 and LIMK2 are key downstream targets to mediate the effects of the Rho family small GTPases and p21-activated kinases (PAK) in the regulation of the actin cytoskeleton. LIMKs are also critical for synaptic transmission, plasticity and memory formation. Changes in LIMK signaling are associated...

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Detalles Bibliográficos
Autores principales: Mao, Rui, Deng, Rui, Wei, Yan, Han, Lifang, Meng, Yanghong, Xie, Wei, Jia, Zhengping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637558/
https://www.ncbi.nlm.nih.gov/pubmed/31319858
http://dx.doi.org/10.1186/s13041-019-0487-7