Cargando…

Oncolytic Maraba virus armed with tumor antigen boosts vaccine priming and reveals diverse therapeutic response patterns when combined with checkpoint blockade in ovarian cancer

BACKGROUND: Cancer immunotherapies are emerging as promising treatment strategies for ovarian cancer patients that experience disease relapse following first line therapy. As such, identifying strategies to bolster anti-tumor immunity and limit immune suppression, while recognizing diverse patterns...

Descripción completa

Detalles Bibliográficos
Autores principales: McGray, A. J. Robert, Huang, Ruea-Yea, Battaglia, Sebastiano, Eppolito, Cheryl, Miliotto, Anthony, Stephenson, Kyle B., Lugade, Amit A., Webster, Gill, Lichty, Brian D., Seshadri, Mukund, Kozbor, Danuta, Odunsi, Kunle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637574/
https://www.ncbi.nlm.nih.gov/pubmed/31315674
http://dx.doi.org/10.1186/s40425-019-0641-x