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Cited2 regulates proliferation and survival in young and old mouse cardiac stem cells

BACKGROUND: Cardiac stem cells (CSCs) exhibit age-dependent characteristics. Cited2 has been implicated in the regulation of heart development; however, there is little known about how Cited2 affects CSC aging. RESULTS: Cited2 mRNA and protein level was downregulated in aging heart tissue and CSCs....

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Detalles Bibliográficos
Autores principales: Wu, Qiong, Liu, Qin, Zhan, Jinxi, Wang, Qian, Zhang, Daxiu, He, Shuangli, Pu, Shiming, Zhou, Zuping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637580/
https://www.ncbi.nlm.nih.gov/pubmed/31315556
http://dx.doi.org/10.1186/s12860-019-0207-2