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mTORC1/AMPK responses define a core gene set for developmental cell fate switching

BACKGROUND: Kinases mTORC1 and AMPK act as energy sensors, controlling nutrient responses and cellular growth. Changes in nutrient levels affect diverse transcriptional networks, making it challenging to identify downstream paths that regulate cellular growth or a switch to development via nutrient...

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Detalles Bibliográficos
Autores principales: Jaiswal, Pundrik, Kimmel, Alan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637605/
https://www.ncbi.nlm.nih.gov/pubmed/31319820
http://dx.doi.org/10.1186/s12915-019-0673-1