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Diverse immunotherapies can effectively treat syngeneic brainstem tumors in the absence of overt toxicity

BACKGROUND: Immunotherapy has shown remarkable clinical promise in the treatment of various types of cancers. However, clinical benefits derive from a highly inflammatory mechanism of action. This presents unique challenges for use in pediatric brainstem tumors including diffuse intrinsic pontine gl...

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Detalles Bibliográficos
Autores principales: Schuelke, Matthew R., Wongthida, Phonphimon, Thompson, Jill, Kottke, Timothy, Driscoll, Christopher B., Huff, Amanda L., Shim, Kevin G., Coffey, Matt, Pulido, Jose, Evgin, Laura, Vile, Richard G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637625/
https://www.ncbi.nlm.nih.gov/pubmed/31315671
http://dx.doi.org/10.1186/s40425-019-0673-2