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miR-451 Silencing Inhibited Doxorubicin Exposure-Induced Cardiotoxicity in Mice

Oxidative stress and cardiomyocytes apoptosis were closely involved in the pathological process of doxorubicin- (Dox-) induced cardiac injury. MicroRNA-451 (miR-451) was mainly expressed in cardiomyocytes. However, the role of miR-451 in Dox-induced cardiac injury remained unclear. Our study aimed t...

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Detalles Bibliográficos
Autores principales: Li, Jun, Wan, Weiguo, Chen, Tao, Tong, Suiyang, Jiang, Xuejun, Liu, Wanli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637715/
https://www.ncbi.nlm.nih.gov/pubmed/31355248
http://dx.doi.org/10.1155/2019/1528278