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Determining the Relationship Between Hot Flushes and LH Pulses in Menopausal Women Using Mathematical Modeling

BACKGROUND: Hypothalamic kisspeptin/neurokinin B/dynorphin (KNDy) neurones regulate LH pulsatility. It is widely accepted that the menopausal hot flush (HF) consistently synchronizes with the LH pulse, implicating the hypothalamic KNDy neurones in generating LH pulsatility and HF. Using a modern imm...

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Detalles Bibliográficos
Autores principales: Prague, Julia K, Voliotis, Margaritis, Clarke, Sophie, Comninos, Alexander N, Abbara, Ali, Jayasena, Channa N, Roberts, Rachel E, Yang, Lisa, Veldhuis, Johannes D, Tsaneva-Atanasova, Krasimira, McArdle, Craig A, Dhillo, Waljit S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637789/
https://www.ncbi.nlm.nih.gov/pubmed/30985867
http://dx.doi.org/10.1210/jc.2018-02797