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Determining the Relationship Between Hot Flushes and LH Pulses in Menopausal Women Using Mathematical Modeling
BACKGROUND: Hypothalamic kisspeptin/neurokinin B/dynorphin (KNDy) neurones regulate LH pulsatility. It is widely accepted that the menopausal hot flush (HF) consistently synchronizes with the LH pulse, implicating the hypothalamic KNDy neurones in generating LH pulsatility and HF. Using a modern imm...
Autores principales: | Prague, Julia K, Voliotis, Margaritis, Clarke, Sophie, Comninos, Alexander N, Abbara, Ali, Jayasena, Channa N, Roberts, Rachel E, Yang, Lisa, Veldhuis, Johannes D, Tsaneva-Atanasova, Krasimira, McArdle, Craig A, Dhillo, Waljit S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Endocrine Society
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637789/ https://www.ncbi.nlm.nih.gov/pubmed/30985867 http://dx.doi.org/10.1210/jc.2018-02797 |
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