Parthenolide Inhibits the Proliferation of MDA-T32 Papillary Thyroid Carcinoma Cells in Vitro and in Mouse Tumor Xenografts and Activates Autophagy and Apoptosis by Downregulation of the Mammalian Target of Rapamycin (mTOR)/PI3K/AKT Signaling Pathway

BACKGROUND: This study aimed to examine the effects of the sesquiterpene lactone, parthenolide, on migration, autophagy, and apoptosis of MDA-T32 human papillary thyroid carcinoma cells in vitro and in mouse tumor xenografts. MATERIAL/METHODS: Cell proliferation and viability of MDA-T32 human papill...

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Detalles Bibliográficos
Autores principales: Li, Chao, Zhou, Yuqiu, Cai, Yongcong, Shui, Chunyan, Liu, Wei, Wang, Xu, Jiang, Jian, Zeng, Dingfen, Gui, Chunhan, Sun, Ronghao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Lab/In Vitro Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637819/
https://www.ncbi.nlm.nih.gov/pubmed/31322140
http://dx.doi.org/10.12659/MSM.915387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637819/
https://www.ncbi.nlm.nih.gov/pubmed/31322140
http://dx.doi.org/10.12659/MSM.915387

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