Identification and design of novel small molecule inhibitors against MERS-CoV papain-like protease via high-throughput screening and molecular modeling

The development of new therapeutic agents against the coronavirus causing Middle East Respiratory Syndrome (MERS) is a continuing imperative. The initial MERS-CoV epidemic was contained entirely through public health measures, but episodic cases continue, as there are currently no therapeutic agents...

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Detalles Bibliográficos
Autores principales: Lee, Hyun, Ren, Jinhong, Pesavento, Russell P., Ojeda, Isabel, Rice, Amy J., Lv, Haining, Kwon, Youngjin, Johnson, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6638567/
https://www.ncbi.nlm.nih.gov/pubmed/30940566
http://dx.doi.org/10.1016/j.bmc.2019.03.050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6638567/
https://www.ncbi.nlm.nih.gov/pubmed/30940566
http://dx.doi.org/10.1016/j.bmc.2019.03.050

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