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Identification and design of novel small molecule inhibitors against MERS-CoV papain-like protease via high-throughput screening and molecular modeling

The development of new therapeutic agents against the coronavirus causing Middle East Respiratory Syndrome (MERS) is a continuing imperative. The initial MERS-CoV epidemic was contained entirely through public health measures, but episodic cases continue, as there are currently no therapeutic agents...

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Detalles Bibliográficos
Autores principales:	Lee, Hyun, Ren, Jinhong, Pesavento, Russell P., Ojeda, Isabel, Rice, Amy J., Lv, Haining, Kwon, Youngjin, Johnson, Michael E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Science 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6638567/ https://www.ncbi.nlm.nih.gov/pubmed/30940566 http://dx.doi.org/10.1016/j.bmc.2019.03.050

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